Primate Tissues
نویسندگان
چکیده
A B S T R A C T The specific activity of the branchedchain a-keto acid (BCKA) dehydrogenases was measured in normal tissues of the rat, monkey, and man, and in cirrhotic human liver. In the rat, specific activity of the dehydrogenases in liver, kidney, and muscle averaged 33, 26, and 0.4 U/g wet tissue, respectively; proportion of the body's content of the enzyme located in these three organs was 70, 12, and 10%. In the monkey, specific activities in liver and kidney were only one-half to one-third as great as in the rat, whereas activity in muscle was the same; the monkey's body content of dehydrogenase was distributed 50% in liver, 13% in kidney, and 20% in muscle. In man, specific activities in liver and kidney were only 1/15th to 1/25th as great as in the rat, but activity in skeletal muscle was the same. Distribution of the dehydrogenases in man was 30% in liver, 2% in kidneys, and 60% in muscle. In six patients with alcoholic cirrhosis, specific activity of the dehydrogenase in liver was reduced to 20-50% of normal (average, 32%). This reduction may alter the efficiency of BCKA as substitutes for branched-chain amino acids when BCKA are administered orally, but will have little influence on efficiency when they are given intravenously.
منابع مشابه
Detection, Cloning, Molecular Characterization and Phylogenic Analyses of a New Primate T-Cell Lymphotropic Virus Type I in Olive Baboon
متن کامل
تأثیر بخش خدمات بر شکل‌گیری پدیده نخست‌شهری در استان خوزستان
In the literature of urban economics, primate city is a phenomenon that a very large city is formed among small cities in urban system of a region that a major part of population and its economic activities of that region is concentrated in it. According to urban economics theories, GFP is one of the factors that can be influential in forming a primate city phenomenon. Given service sector in t...
متن کاملI-34: Endometrial Secretome and Its Role in Uterine Functions
Background Earlier it was believed that uterine fluid (UF) or secretions are not relevant after the embryo implantation in humans. However, recent reports suggest that uterine secretions continue to play important role till the first trimester of human pregnancy. Evidences also suggest that uf mirrors endometrial functions or dysfunctions. Considering the relevance of uf in endometrial function...
متن کاملSoft-tissue characters in higher primate phylogenetics.
Recent research has cast doubt on the reliability of bones and teeth for reconstructing phylogenetic relationships among higher primate species and genera. Herein, we investigate whether this problem is confined to hard tissues by examining the utility of higher primate soft-tissue characters for reconstructing phylogenetic relationships at low taxonomic levels. We use cladistic methods to anal...
متن کاملCholic acid accumulation by the ciliary body and by the iris of the primate eye.
Cholic acid accumulates in both the ciliary body and the iris of the primate eye during in vitro incubations at 37 degrees C for 1 hr. Incubation at 0 degrees C depresses uptake in both tissues. The washout of preaccumulated cholic acid occurs some 3.4 times faster from the iris than from the ciliary body. The mechanism of cholic acid accumulation in both tissues is less sensitive to inhibition...
متن کاملO-32: Endometrial Secretome and Its Role in Uterine Functions
Background Earlier it was believed that uterine fluid (uf) or secretions are not relevant after the embryo implantation in humans. However, recent reports suggest that uterine secretions continue to play important role till the first trimester of human pregnancy. Evidences also suggest that uf mirrors endometrial functions or dysfunctions. Considering the relevance of uf in endometrial function...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2003